1. Composition

• Theophylline – 120 mg per tablet
• Ephedrine – 11 mg per tablet

Other inactive ingredients: starch, lactose, magnesium stearate, etc.

Drug class:

• Bronchodilator combination
• Theophylline: xanthine derivative
• Ephedrine: sympathomimetic amine

2. Uses / Indications

Asmanol tablets are used for:

• Relief and prevention of bronchospasm
• Asthma management
• Chronic bronchitis and COPD
• Wheezing, shortness of breath, and airway obstruction

Mechanism of action:

• Theophylline: relaxes bronchial smooth muscles, improves airflow, mild anti-inflammatory effect
• Ephedrine: stimulates β2-adrenergic receptors, causing bronchodilation and opening of airways

3. Direction for Use

(Dosage depends on doctor’s prescription)

• Adults: usually 1 tablet 2–3 times daily
• Children: dose adjusted by age/weight by a healthcare professional
• Take orally with water, with or after food to reduce stomach irritation

4. Side Effects

Common side effects:

• Tremors or shakiness
• Nervousness, restlessness
• Headache
• Palpitations or fast heartbeat
• Nausea, vomiting, stomach upset
• Insomnia

Serious side effects (rare):

• Irregular heartbeat (arrhythmia)
• Seizures (with high theophylline levels)
• High blood pressure (from ephedrine)

5. Warnings / Interactions / Cautions

• Do not exceed recommended dose
• Use cautiously in patients with:
• Heart disease or arrhythmia
• High blood pressure
• Hyperthyroidism
• Seizure disorders
• Diabetes

• Interactions with:
• Other sympathomimetics, beta-blockers, theophylline-containing medications, caffeine
• Avoid in pregnancy or breastfeeding unless prescribed
• Monitor for signs of overdosage: severe tremors, palpitations, nausea, vomiting, confusion