PRODUCT DETAILS

Composition

• Esomeprazole 40 mg
• Drug class: Proton Pump Inhibitor (PPI)

Uses / Indications

Used to reduce stomach acid in conditions such as:

• Gastroesophageal reflux disease (GERD/acid reflux)
• Heartburn
• Gastric and duodenal ulcers
• Gastritis
• Prevention of ulcers caused by NSAIDs (e.g., diclofenac)
• Part of treatment for Helicobacter pylori infection (combined with antibiotics)
• Zollinger–Ellison syndrome

Direction for Use

• Usually taken once daily
• Best taken 30–60 minutes before meals, especially before breakfast
• Swallow capsule/tablet whole
• Do not crush or chew enteric-coated forms
• Duration depends on condition being treated

Side Effects

Common:

• Headache
• Nausea
• Abdominal pain
• Diarrhea or constipation
• Gas/bloating

Less common:

• Dizziness
• Dry mouth

Long-term / serious risks:

• Low magnesium levels
• Vitamin B12 deficiency
• Increased risk of fractures (long-term use)
• Kidney problems
• Increased risk of certain intestinal infections

Warnings

• Long-term use should be medically supervised
• May mask symptoms of serious stomach disease
• Use caution in severe liver disease
• Do not use unnecessarily for long periods

Interactions

May interact with:

• Clopidogrel (may reduce effectiveness)
• Warfarin
• Iron supplements (reduced absorption)
• Certain antifungals requiring stomach acid for absorption
• Methotrexate (high-dose)

Cautions

Use carefully in:

• Elderly patients
• Liver disease
• Patients on long-term therapy
• Patients with osteoporosis risk

Monitoring may be needed for prolonged use:

• Magnesium
• Vitamin B12
• Kidney function