PRODUCT DETAILS

Composition

Each capsule contains:

• Paracetamol 500 mg (pain and fever relief)
• Promethazine hydrochloride 10 mg (sedating antihistamine)
• Dextromethorphan hydrobromide 7.5 mg (cough suppressant)

These act together to relieve night-time cold and flu symptoms.

Uses / Indications

• Relief of cold and flu symptoms at night
• Dry cough suppression
• Fever and body aches
• Runny nose and sneezing
• Helps with sleep during illness due to sedative effect

Direction of Use

• Adults and children 16 years and over
• Usual dose: 2 capsules at bedtime
• Only one dose per night
• Short-term use only (typically max 3 nights without medical advice)
• Swallow with water

Side Effects

Common or possible effects:

• Drowsiness (very common)
• Dizziness
• Dry mouth
• Blurred vision
• Nausea or stomach discomfort
• Morning grogginess

Less common but serious:

• Confusion or hallucinations
• Fast or irregular heartbeat
• Allergic reactions (rash, swelling)
• Difficulty passing urine
• Respiratory depression (rare, overdose risk)

Warnings / Precautions

• May cause strong sedation → avoid driving or machinery
• Do not use with alcohol
• Contains paracetamol → avoid other paracetamol products (liver risk)
• Contains promethazine → can cause heavy drowsiness and confusion
• Risk of interaction with:
• antidepressants (SSRIs/MAOIs)
• other antihistamines
• sedatives or sleeping tablets
• Not suitable for:
• children under 16 years
• people with severe breathing problems (asthma, COPD flare)
• MAOI use within last 14 days
• Use caution in elderly due to confusion risk

Drug Interactions

• MAO inhibitors (dangerous interaction)
• SSRIs / SNRIs / tricyclic antidepressants (serotonin syndrome risk with dextromethorphan)
• Alcohol (increased sedation and liver strain)
• Other antihistamines or sedatives
• Other paracetamol-containing products

Contraindications / Caution

Avoid if:

• Allergy to paracetamol, promethazine, or dextromethorphan
• Severe respiratory disease or breathing failure
• Recent MAOI use (within 14 days)
• Severe liver disease
• High risk of urinary retention or glaucoma