PRODUCT DETAILS

Composition

• Active ingredients:
• Artemether 80 mg
• Lumefantrine 480 mg
• Drug class: Antimalarial combination therapy (ACT)

Uses / Indications

Used for:

• Treatment of uncomplicated malaria caused by Malaria
• Especially effective against Plasmodium falciparum infections

It is not usually used for severe malaria requiring hospital treatment.

Direction for Use

• Usually taken twice daily for 3 days as prescribed
• Best taken with food or milk, especially fatty food, to improve absorption
• Swallow tablets with water
• Complete the full treatment course even if symptoms improve
• If vomiting occurs shortly after taking a dose, another dose may be needed

Side Effects

Common side effects:

• Headache
• Dizziness
• Weakness
• Loss of appetite
• Nausea or vomiting
• Abdominal pain
• Muscle or joint pain

Serious side effects:

• Irregular heartbeat
• Severe allergic reaction
• Fainting
• Severe skin reactions

Warnings

• May affect heart rhythm (QT prolongation)
• Use cautiously in patients with heart disease
• Avoid use with other medicines that affect heart rhythm unless prescribed
• Not recommended for severe malaria cases without medical supervision

Interactions

May interact with:

• Other antimalarial drugs
• Certain antibiotics (e.g., erythromycin)
• Antifungal medicines
• HIV medications
• Anti-arrhythmics
• Seizure medications
• Grapefruit juice (may alter drug levels)

Cautions / Precautions

Use cautiously in:

• Pregnancy (especially first trimester unless prescribed)
• Liver disease
• Heart rhythm disorders
• Patients with low potassium or magnesium

Important precautions:

• Take with food for best effect
• Seek medical care if symptoms worsen or return after treatment
• Monitor for persistent fever or signs of severe malaria
• Avoid skipping doses to reduce resistance risk