PRODUCT DETAILS

Composition

Each gram contains:

• Neomycin sulfate (antibiotic – aminoglycoside)
• Polymyxin B sulfate (antibiotic)
• Dexamethasone (corticosteroid 0.1%)

Category / Class

• Ophthalmic combination drug:
• Antibiotics + Corticosteroid
• Anti-infective + anti-inflammatory eye ointment

Use / Indications

Used for eye conditions where infection risk + inflammation coexist, such as:

• Bacterial conjunctivitis with inflammation
• Blepharitis (eyelid inflammation)
• Keratitis (non-viral causes)
• Anterior uveitis (in some cases)
• Post-operative eye inflammation
• Eye injury with risk of bacterial infection

Direction of Use

Typical dosing:

• Apply a small amount (about 1 cm ribbon) into the lower eyelid (conjunctival sac)
• Usually 3–4 times daily
• May be used with eye drops during the day and ointment at night
• Do not touch tube tip to eye
• Wash hands before use

Side Effects

Common

• Temporary blurred vision (very common due to ointment base)
• Mild eye irritation or burning
• Eye discomfort

Important / Serious

• Increased intraocular pressure → risk of glaucoma
• Cataract formation with prolonged use
• Delayed wound healing
• Secondary infections (bacterial, fungal, viral)
• Allergic reaction (especially to neomycin)
• Masking or worsening of viral eye infections

Warnings

Do NOT use in:

• Viral eye infections (e.g., herpes simplex)
• Fungal eye infections
• Tuberculosis or untreated parasitic eye infections
• Known allergy to neomycin, polymyxin B, or steroids

Important:

• Steroid may worsen hidden infections
• Long-term use requires eye pressure monitoring (risk of glaucoma)
• Can thin the cornea in prolonged use

Drug Interactions

• Minimal systemic interactions (low absorption)
• Caution with:
• Other steroid eye drops
• Other eye antibiotics
• Drugs that increase infection risk or immune suppression

Cautions

• Short-term use only unless supervised
• Avoid contact lens use during treatment
• May blur vision → avoid driving immediately after use
• Prolonged use increases risk of serious eye complications
• Stop and seek review if symptoms worsen after 48 hours