PRODUCT DETAILS

Composition

Each gram contains:

• Tobramycin 0.3% (3 mg/g)
• Dexamethasone 0.1% (1 mg/g)

Category / Class

• Ophthalmic antibiotic + corticosteroid combination
• Aminoglycoside antibiotic + steroid eye ointment

Use / Indications

Used for:

• Steroid-responsive inflammatory eye conditions with bacterial infection or risk of infection
• Bacterial conjunctivitis with inflammation
• Blepharitis
• Keratitis (non-viral)
• Chronic anterior uveitis
• Post-operative eye inflammation
• Corneal injury from burns, radiation, or foreign bodies

Mechanism of Action

• Tobramycin kills susceptible bacteria causing eye infections.
• Dexamethasone suppresses inflammation, reducing redness, swelling, itching, and pain.

Direction of Use

Typical dosage:

• Apply approximately a ½-inch ribbon into the conjunctival sac
• Usually 3–4 times daily or as prescribed

Instructions:

• Wash hands before use
• Pull lower eyelid down gently and apply ointment
• Avoid touching tube tip to eye or skin
• Close eyes gently for 1–2 minutes after application
• Vision may blur temporarily after use
• If also using eye drops, apply drops first and ointment last after 5–10 minutes

Common Side Effects

• Temporary blurred vision
• Burning or stinging sensation
• Eye irritation or discomfort
• Eyelid itching/swelling
• Redness
• Watery eyes

Serious Side Effects

Especially with prolonged use:

• Increased intraocular pressure (glaucoma)
• Cataract formation
• Optic nerve damage
• Delayed wound healing
• Secondary fungal, bacterial, or viral infections
• Corneal thinning or perforation
• Severe allergic reactions/anaphylaxis

Warnings

Do NOT use in:

• Viral eye infections (especially herpes simplex)
• Fungal eye infections
• Mycobacterial eye infections
• Allergy to aminoglycosides, tobramycin, dexamethasone, or corticosteroids

Important warnings:

• Prolonged steroid use may increase eye pressure and cause glaucoma
• Steroids may mask worsening infections
• Long-term use requires ophthalmic monitoring
• Corneal thinning/perforation risk increases with prolonged use

Drug Interactions

Use cautiously with:

• Other steroid eye medications
• Other aminoglycoside antibiotics
• Immunosuppressants
• CYP3A4 inhibitors (may increase steroid-related effects in susceptible patients)

Cautions

• Temporary blurred vision may impair driving
• Avoid contact lenses during active infection
• Avoid prolonged unsupervised use
• Use cautiously in glaucoma patients
• Use cautiously in diabetes and dry eye disease
• Paediatric safety below age 2 years is not established