PRODUCT DETAILS

Composition

• Paracetamol (Acetaminophen) 250 mg per suppository.

Category / Class

• Analgesic (pain reliever)
• Antipyretic (fever reducer)

Use / Indications

Used for:

• Fever
• Mild to moderate pain
• Toothache
• Headache
• Pain associated with common childhood illnesses
• Patients who cannot take oral tablets or syrup due to vomiting or difficulty swallowing.

Mechanism of Action

Paracetamol works by:

• Reducing the production of pain signals in the brain.
• Acting on the temperature-regulating center of the brain to reduce fever.

Direction of Use

• For rectal use only.
• Remove the wrapper and gently insert the suppository into the rectum.
• Dosage depends on age and body weight.

Examples:

• Children around 20 kg (about 5 years): One 250 mg suppository every 4–6 hours as needed, not exceeding 4 doses in 24 hours.

Common Side Effects

Paracetamol suppositories are generally well tolerated, but may cause:

• Mild rectal irritation
• Redness around the rectal area
• Skin rash
• Allergic reactions (rare)

Serious Side Effects

Seek medical attention if:

• Severe allergic reaction
• Swelling of the face, lips, or throat
• Difficulty breathing
• Severe skin rash
• Signs of liver injury (yellow eyes, dark urine, severe nausea)

Warnings

Do NOT use:

• If allergic to paracetamol.
• Together with other paracetamol-containing medicines unless advised by a healthcare professional.
• In doses higher than recommended.

Drug Interactions

Use cautiously with:

• Other products containing paracetamol
• Warfarin (long-term regular use may increase anticoagulant effect)
• Certain medicines affecting liver function

Cautions

• Use with caution in liver disease.
• Use with caution in severe kidney disease.
• Store below 25°C and protect from heat.
• If fever lasts more than 3 days or pain persists, seek medical advice.

Pregnancy & Breastfeeding

• The 250 mg suppository is primarily intended for children. Adults who require paracetamol during pregnancy or breastfeeding should consult a healthcare professional regarding appropriate dosage and formulation.