PRODUCT DETAILS
Composition
Uses / Indication
Neuropathic pain (e.g., due to diabetes, spinal cord injury)
Fibromyalgia
Epilepsy (as adjunctive therapy for partial seizures)
Generalized Anxiety Disorder (GAD) (in some countries)
Postherpetic neuralgia (pain following shingles)
Direction of Use
Taken orally, usually 1 to 2 times per day as prescribed
Dosage depends on the condition being treated and patient response
Can be taken with or without food
Dose should be adjusted gradually to avoid side effects
Do not stop suddenly; tapering is necessary to prevent withdrawal symptoms (e.g., insomnia, nausea, headache)
Side Effects
Common:
Dizziness
Drowsiness or fatigue
Blurred vision
Weight gain
Swelling of hands and feet (peripheral oedema)
Serious:
Suicidal thoughts or behaviour
Allergic reactions (rash, difficulty breathing, swelling)
Angioedema (swelling of the face, mouth, or throat)
Withdrawal symptoms if stopped abruptly
Rare cases of rhabdomyolysis (muscle breakdown)
Warnings:
May cause dizziness and sleepiness; caution with activities requiring alertness (e.g., driving)
Risk of abuse and dependence, especially in patients with a history of substance abuse
Dose adjustment may be necessary in patients with kidney impairment
Drug Interactions:
Increased sedative effects with alcohol, opioids, benzodiazepines, and other CNS depressants
May enhance the effects of certain antidiabetic drugs (risk of peripheral oedema)
Use caution with drugs that depress the central nervous system
Cautions:
Not recommended during pregnancy unless clearly needed; animal studies have shown potential risks
Use during breastfeeding should be evaluated by a healthcare provider
Elderly patients may be more sensitive to side effects like dizziness and unsteadiness
